Method 1: Solving the DLL Error by Copying the Pythoncom22.dll File to the Windows System Folder 

1. The file you are going to download is a compressed file with the ".zip" extension. You cannot directly install the ".zip" file. First, you need to extract the dll file from inside it. So, double-click the file with the ".zip" extension that you downloaded and open the file.
2. You will see the file named "Pythoncom22.dll" in the window that opens up. This is the file we are going to install. Click the file once with the left mouse button. By doing this you will have chosen the file.

   

3. Click the "Extract To" symbol marked in the picture. To extract the dll file, it will want you to choose the desired location. Choose the "Desktop" location and click "OK" to extract the file to the desktop. In order to do this, you need to use the Winrar software. If you do not have this software, you can find and download it through a quick search on the Internet.

   

4. Copy the "Pythoncom22.dll" file you extracted and paste it into the "C:\Windows\System32" folder.

   

5. If your operating system has a 64 Bit architecture, copy the "Pythoncom22.dll" file and paste it also into the "C:\Windows\sysWOW64" folder.

   NOTE! On 64 Bit systems, the dll file must be in both the "sysWOW64" folder as well as the "System32" folder. In other words, you must copy the "Pythoncom22.dll" file into both folders.

   

6. In order to run the Command Line as an administrator, complete the following steps.

   NOTE! In this explanation, we ran the Command Line on Windows 10. If you are using one of the Windows 8.1, Windows 8, Windows 7, Windows Vista or Windows XP operating systems, you can use the same methods to run the Command Line as an administrator. Even though the pictures are taken from Windows 10, the processes are similar.

   1. First, open the Start Menu and before clicking anywhere, type "cmd" but do not press Enter.
   2. When you see the "Command Line" option among the search results, hit the "CTRL" + "SHIFT" + "ENTER" keys on your keyboard.
   3. A window will pop up asking, "Do you want to run this process?". Confirm it by clicking to "Yes" button.

   

7. Paste the command below into the Command Line that will open up and hit Enter. This command will delete the damaged registry of the Pythoncom22.dll file (It will not delete the file we pasted into the System32 folder; it will delete the registry in Regedit. The file we pasted into the System32 folder will not be damaged).

   %windir%\System32\regsvr32.exe /u Pythoncom22.dll

   

8. If you are using a Windows version that has 64 Bit architecture, after running the above command, you need to run the command below. With this command, we will clean the problematic Pythoncom22.dll registry for 64 Bit (The cleaning process only involves the registries in Regedit. In other words, the dll file you pasted into the SysWoW64 will not be damaged).

   %windir%\SysWoW64\regsvr32.exe /u Pythoncom22.dll

   

9. You must create a new registry for the dll file that you deleted from the registry editor. In order to do this, copy the command below and paste it into the Command Line and hit Enter.

   %windir%\System32\regsvr32.exe /i Pythoncom22.dll

   

10. If you are using a 64 Bit operating system, after running the command above, you also need to run the command below. With this command, we will have added a new file in place of the damaged Pythoncom22.dll file that we deleted.

    %windir%\SysWoW64\regsvr32.exe /i Pythoncom22.dll

    

11. If you did all the processes correctly, the missing dll file will have been installed. You may have made some mistakes when running the Command Line processes. Generally, these errors will not prevent the Pythoncom22.dll file from being installed. In other words, the installation will be completed, but it may give an error due to some incompatibility issues. You can try running the program that was giving you this dll file error after restarting your computer. If you are still getting the dll file error when running the program, please try the 2nd method.

Method 2: Copying The Pythoncom22.dll File Into The Software File Folder 

1. In order to install the dll file, you need to find the file folder for the software that was giving you errors such as "Pythoncom22.dll is missing", "Pythoncom22.dll not found" or similar error messages. In order to do that, Right-click the software's shortcut and click the Properties item in the right-click menu that appears.

   

2. Click on the Open File Location button that is found in the Properties window that opens up and choose the folder where the application is installed.

   

3. Copy the Pythoncom22.dll file into the folder we opened up.

   

4. That's all there is to the installation process. Run the software giving the dll error again. If the dll error is still continuing, completing the 3rd Method may help solve your problem.

Method 3: Uninstalling and Reinstalling the Software That Is Giving the Pythoncom22.dll Error 

1. Push the "Windows" + "R" keys at the same time to open the Run window. Type the command below into the Run window that opens up and hit Enter. This process will open the "Programs and Features" window.

   appwiz.cpl

   

2. The softwares listed in the Programs and Features window that opens up are the softwares installed on your computer. Find the software that gives you the dll error and run the "Right-Click > Uninstall" command on this software.

   

3. Following the instructions that come up, uninstall the software from your computer and restart your computer.

   

4. After restarting your computer, reinstall the software that was giving the error.
5. You may be able to solve the dll error you are experiencing by using this method. If the error messages are continuing despite all these processes, we may have a problem deriving from Windows. To solve dll errors deriving from Windows, you need to complete the 4th Method and the 5th Method in the list.

Method 4: Solving the Pythoncom22.dll Problem by Using the Windows System File Checker (scf scannow) 

1. In order to run the Command Line as an administrator, complete the following steps.

   NOTE! In this explanation, we ran the Command Line on Windows 10. If you are using one of the Windows 8.1, Windows 8, Windows 7, Windows Vista or Windows XP operating systems, you can use the same methods to run the Command Line as an administrator. Even though the pictures are taken from Windows 10, the processes are similar.

   1. First, open the Start Menu and before clicking anywhere, type "cmd" but do not press Enter.
   2. When you see the "Command Line" option among the search results, hit the "CTRL" + "SHIFT" + "ENTER" keys on your keyboard.
   3. A window will pop up asking, "Do you want to run this process?". Confirm it by clicking to "Yes" button.

   

2. Paste the command below into the Command Line that opens up and hit the Enter key.

   sfc /scannow

   

3. This process can take some time. You can follow its progress from the screen. Wait for it to finish and after it is finished try to run the software that was giving the dll error again.

Method 5: Getting Rid of Pythoncom22.dll Errors by Updating the Windows Operating System 

Most of the time, softwares have been programmed to use the most recent dll files. If your operating system is not updated, these files cannot be provided and dll errors appear. So, we will try to solve the dll errors by updating the operating system.

Since the methods to update Windows versions are different from each other, we found it appropriate to prepare a separate article for each Windows version. You can get our update article that relates to your operating system version by using the links below.

Windows Update Guides 

1. Windows Update Guide
2. Windows 8.1 and Windows 8 Update Guide
3. Windows 7 and Windows Vista Update Guide
4. Windows XP Update Guide